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Childhood Nephrotic Syndrome - What is Nephrotic Syndrome?



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Nephrotic syndrome occurs when the kidneys leak large amounts of protein (mostly albumin) into the urine. Protein lost in the urine results in a lower level of proteins in the blood. It is these proteins in the blood which help to hold water within the blood vessels. Therefore, when the protein level is very low, water passes into the tissues and this is recognised as swelling (oedema).

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Content compiled by members of the Children’s Renal & Urology Unit, QMC Campus, Nottingham University Hospitals.

The National Kidney Federation cannot accept responsibility for information provided. The above is for guidance only. Patients are advised to seek further information from their own doctor.

NKF Controlled Document No. 130: What is Nephrotic Syndrome? written: 10/09/2004 last reviewed: 14/11/2020